I found the issue the msvcr140.dll missing and need to install Visual C++ Redistributable for Visual Studio 2015 then Microsoft Visual C++ 2015 Redistributable Update 3 and restart.
Run the .mis installer and it should complete.
At this point make sure the Synergy 2 APP is running in Administrator under the Compatibility tab on the Windows 7 system.
On the Prime system shut down Synergy 2 APP disable the Windows Firewall completely go in to the services.msc and restart the Synergy 2 service then start the Synergy 2 APP.
Re-enable the Windows Firewall and you should be good to go.
The Windows 7 Synergy 2 APP screen will look like crap but it is running.
On the Prime system the Windows 7 system may keep looking like it is loading in the Synergy 2 APP screen but so far I have no issue going from screen to screen.
Hope this helps those of you with Windows 7 64-bit systems.
Visual C++ Redistributable for Visual Studio 2015 https://www.microsoft.com/en-us/download/details.aspx?id=48145
Microsoft Visual C++ 2015 Redistributable Update 3 https://www.microsoft.com/en-us/download/details.aspx?id=53587